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KMID : 1007520160250010267
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Food Science and Biotechnology
2016 Volume.25 No. 1 p.267 ~ p.273
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Aged Ginseng (Panax ginseng Meyer) Reduces Blood Glucose Levels and Improves Lipid Metabolism in High Fat Diet-fed Mice
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Chung Soo-Im
Nam Su-Jin
Xu Mingze
Kang Mi-Young
Lee Sang-Chul
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Abstract
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Aged ginseng is unpeeled ginseng root that has been dried and heat-treated in an oven at 80°C for 14 days. The effects of aged ginseng, in comparison with white and red ginseng, on the lipid and glucose metabolism in high fat-fed mice were investigated. C57BL/6N mice were randomly divided into six dietary groups of normal control, high fat, and high fat supplemented with white, red, aged four-year old, and aged five-year old ginseng. After 8 weeks, ginseng counteracted high fat diet-induced body weight gain, hyperlipidemia, and hyperglycemia via a mechanism involving modulation of hepatic lipogenesis, adipokine production, and glucose-regulating enzyme activities. Aged ginseng showed greater antihyperlipidemic and antihyperglycemic activities than white ginseng and exhibited physiological effects similar to red ginseng, perhaps due to a relatively high ginsenoside content. Aged ginseng can be beneficial as a functional food.
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KEYWORD
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aged ginseng, red, lipid, glucose
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